ABSTRACT Frontotemporal dementia is the second most common cause of dementia in the general population between 45 and 64-year-olds. Frontotemporal dementia is usually presented with behavioural and personality changes, executive dysfunctions and language difficulties. In the beginning of disease, the clinical picture of frontotemporal dementia is very heterogeneous and it may have atypical presentations like psychotic symptoms. It was reported that %13–14 cases of frontotemporal dementia had psychotic symptoms at the onset or during the course of diagnosis. The overlapping symptoms between psychosis and frontotemporal dementia may worsen the prognosis of disease. Here we describe a case of frontotemporal dementia with psychotic symptoms. Case presentation: A 59-year-old, female patient with auditory and visual hallucinations, delusion of persecution, aggressiveness to her husband, aphasia, phonemic paraphasia was admitted to our outpatient clinic. His psychiatric symptoms dated 2 years ago and represented with hallucinations and delusions. 9 years ago, she had diagnosed with Alzheimer’s disease because of progressive amnesia. After she diagnosed with Alzheimer’s disease, she put on treatment with memantine 10 mg/day and piracetam 800 mg/day. 5 years ago, the symptoms of aphasia, hypophonia, phonemic paraphasia were found with her progressive amnesia. But her symptoms were fluctuating over time with treatment. 2 years ago, hallucinations like talking with stranger people not to give a harm to children whom she met, were added her symptoms. Her first psychiatric presentation and admission was at the age of 57 with hallucinations and delusional symptoms. The escitalopram 20 mg/day and mirtazapine 30 mg/day treatments were added in her memantine and piracetam treatments. But patient’s symptoms were leading disturbance in functionality with progressive pattern. Because of aphasia, paraphasia, and psychotic symptoms and aggressiveness to her relatives, functionality of patient was disturbed seriously. Frontotemporal dementia has insidious onset and slow progression. From a clinical point of view, psychiatric symptoms can be seen in every stage of this type of dementia, which usually worsen the prognosis of disease. Because of these reasons, detailed neuropsychiatric approach is necessary for providing comprehensive care to patients.
The upEVIL starts 22 by 23 they'll be coming for YOU!!
